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Pharmacogenetics and Irinotecan Therapy

UGTs are point II enzymes that are part of a superfamily of microsomal enzymes. UGTs are membrane-bound enzymes localized in the endoplasmic second stomach of person and extrahepatic tissues. Glucuronidation of endogenous and exogenous compounds facilitates their analysis via the biliary and urinary tracts. This voiding is characterized by the covalent increase of glucuronic acid to lipophilic ...

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Microsomal

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Pharmacogenetics and Irinotecan Therapy